Why the study?
Does agitation improve agonist-induced aggregation in 48 hours-stored platelet concentrates compared to non-agitation?
Does agitation improve agonist-induced aggregation in 48 hours-stored platelet concentrates compared to non-agitation?
Agitation effects on stored platelet function remain uncertain in animals; leaves open whether agitation improves aggregation in human transfusion.
Platelets (PLTs) transfusion and their efficacy in a recipient depend on PLTs quality and quantity pretransfusion. One of the important aspects of treating PLT concentrates (PCs), which has controversial effect on functionality is storage of the PCs in an active metabolic state during prolonged storage either by (gentle-) agitation or by rotations in the different angels.
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Badlou BA Timori NH (2014) studied this question.
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