Why the study?
Does depression impact self-perceived health status and functional ability in older patients with chronic heart failure?
Does depression impact self-perceived health status and functional ability in older patients with chronic heart failure?
In older patients with chronic heart failure, depression is strongly associated with worse self-perceived health status and reduced functional ability, potentially linked to neuroendocrine and immune dysfunction.
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Depressive symptoms associated with worse outcomes in older HF patients; hypothesis-generating for neuroendocrine links, requires prospective validation.
Zuccalà et al. (1995) studied this question.
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