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July 25, 2007European Respiratory Journal

Estimating pulmonary artery pressures by echocardiography in patients with emphysema

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Why the study?

Does Doppler echocardiography accurately estimate pulmonary artery pressures compared to right heart catheterization in patients with severe emphysema?

Population

163 patients with emphysema being evaluated for lung volume reduction surgery, participating in the…

Comparison

Doppler echocardiography to estimate right… vs Right heart catheterisation to invasively…

Design

Cross-sectional

Authors

MFMicah R. FisherUnited States Institute of PeaceGCGerard J. CrinerThe Wistar InstituteAFA. P. FishmanUniversity Hospital of Lausanne

Discussion

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Implication

Echocardiography shows poor accuracy for pulmonary hypertension in severe emphysema; leaves open need for better noninvasive screening before routine peri-operative use.

Structured PICO

Does Doppler echocardiography accurately estimate pulmonary artery pressures compared to right heart catheterization in patients with severe emphysema?

P
Population
163 patients with emphysema being evaluated for lung volume reduction surgery, participating in the cardiovascular substudy of the National Emphysema Treatment Trial.
I
Intervention
Doppler echocardiography to estimate right ventricular systolic pressures
C
Comparator
Right heart catheterisation to invasively measure pulmonary artery systolic pressures
O
Outcome
Accuracy of echocardiography for diagnosing pulmonary hypertension (sensitivity, specificity, positive predictive value, negative predictive value, bias, and limits of agreement)surrogate

In patients with severe emphysema, echocardiographic estimates of pulmonary artery pressures correlate weakly with right heart catheterization and have poor diagnostic accuracy.

Cite This Study

Fisher et al. (2007) studied this question.

synapsesocial.com/papers/6a8c7da17b1ef46d2ffdf538https://doi.org/10.1183/09031936.00033007
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Doppler echocardiographic evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease. A European multicentre study1991 · 189 citations
  2. 2Clinical classification of pulmonary hypertension2004 · 1,901 citations
  3. 3Rationale and Design of the National Emphysema Treatment Trial1999 · 215 citations
  4. 4Predictive Factors of Hospitalization for Acute Exacerbation in a Series of 64 Patients with Chronic Obstructive Pulmonary Disease1999 · 575 citations