Why the study?
Data were limited regarding differences in clinical outcomes and the efficacy of catheter ablation according to AF duration (paroxysmal vs persistent AF).
Does catheter ablation reduce cardiovascular events compared to medical therapy in patients with paroxysmal or persistent atrial fibrillation?
Does catheter ablation reduce cardiovascular events compared to medical therapy in patients with paroxysmal or persistent atrial fibrillation?
Catheter ablation significantly reduces cardiovascular events in patients with paroxysmal AF, but its prognostic benefit is less clear in those with persistent AF compared to medical therapy.
Persistent AF associated with higher events and limited QoL gains; leaves open whether ablation strategies should differ by AF type.
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A 2025 study studied this question.
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