Why the study?
Does heparin-coating of extracorporeal circuits reduce thrombin formation in patients undergoing cardiopulmonary bypass?
Population
30 patients undergoing coronary artery bypass grafting (CABG)
Comparison
Heparin-coated extracorporeal circuits used… vs Extracorporeal circuits without heparin-coating…
Design
RCT, randomly divided into two groups
Follow-up
Duration of cardiopulmonary bypass
Authors
Loading...
Heparin-coated circuits attenuate early thrombin formation in CPB; confirms systemic anticoagulation remains essential after crossclamp release.
Does heparin-coating of extracorporeal circuits reduce thrombin formation in patients undergoing cardiopulmonary bypass?
Heparin-coated circuits reduce early thrombin formation during cardiopulmonary bypass, but this effect is overcome by material-independent stimuli after aortic crossclamp release, necessitating continued adequate systemic heparinization.
Gu et al. (1991) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: