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June 13, 2017NutrientsOpen Access

Phytosterols and Omega 3 Supplementation Exert Novel Regulatory Effects on Metabolic and Inflammatory Pathways: A Proteomic Study

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Why the study?

Does phytosterol or omega-3 supplementation alter metabolic and inflammatory proteomic pathways in overweight healthy volunteers?

Population

32 overweight healthy volunteers with body mass index (BMI) 25–35 kg/m2

Comparison

Phytosterols-milk or omega-3-milk for 4 weeks vs Basal samples before any intervention

Design

Other

Follow-up

4 weeks

Authors

CLCarmen LambertJCJudit CubedoTPTeresa Padró

Discussion

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Overview

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Structured PICO

Does phytosterol or omega-3 supplementation alter metabolic and inflammatory proteomic pathways in overweight healthy volunteers?

P
Population
32 overweight healthy volunteers with body mass index (BMI) 25–35 kg/m2
I
Intervention
Phytosterols (PhyS)-milk or omega-3 (ω3)-milk for 4 weeks
C
Comparator
Basal samples before any intervention (longitudinal crossover design)
O
Outcome
Changes in proteins in the main lipoproteins (LDL and HDL) and lipid free plasma fraction (LPDP)surrogate

Phytosterol supplementation attenuates pro-inflammatory pathways, whereas omega-3 supplementation improves lipid metabolic pathways in overweight healthy volunteers.

Cite This Study

Lambert et al. (2017) studied this question.

synapsesocial.com/papers/6a8ce0ef0fc8325511ff1564https://doi.org/10.3390/nu9060599
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