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January 1, 2015The Journal of Poultry ScienceOpen Access

Characterization of Avian Encephalomyelitis Outbreaks Occurred in South Korea from 2006 to 2013

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Population

Breeder and commercial chickens in South Korea, including young chickens <4 weeks old and unvaccinated…

Design

Preclinical

Authors

HKHye-Ryoung KimAnimal and Plant Quarantine AgencyYKYong‐Kuk KwonCenters for Disease Control and PreventionHLHee-Soo LeeElectronics and Telecommunications Research Institute

Discussion

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Overview

AE strains genetically similar to vaccine may drive poultry outbreaks; leaves open vaccine breakdown versus persistence mechanisms.

Structured PICO

P
Population
Breeder and commercial chickens in South Korea, including young chickens <4 weeks old and unvaccinated 79-day-old chickens showing neurological signs (ataxia, paralysis).
I
Intervention
Phylogenetic analysis of viral protein 2 genes and embryo-inoculation test via yolk sac of avian encephalomyelitis (AE) viruses.
O
Outcome
Genetic characterization and embryo-adaptation of AE field viruses.

Avian encephalomyelitis outbreaks in South Korea were caused by strains genetically similar to the vaccine strain, suggesting vaccine breakdown or persistence in the chicken population.

Cite This Study

Kim et al. (2015) studied this question.

synapsesocial.com/papers/6a8ce68e8a9f77207c301b43https://doi.org/10.2141/jpsa.0140158
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