Key result
Immunofluorescence detects avian encephalomyelitis antigens persisting in chicken CNS for up to ~36 days.
Why the study?
The persistence and distribution of viral antigens in the central nervous systems of chickens during avian encephalomyelitis outbreaks were not fully characterized.
Population
5-to-40-day-old chickens from about 10 AE outbreaks including symptomatic, asymptomatic, dead-in-shell, and pipped chicks
Comparison
Chicks from vaccinated breeding flocks versus non-vaccinated or naturally infected flocks
Design
Observational ecological survey using immunofluorescent method
Follow-up
11-36 days
Authors
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May support immunofluorescence diagnostics in poultry outbreaks; leaves open pathogenesis and control studies.
Observational
Viral antigens of avian encephalomyelitis can be detected in the CNS of infected chickens using immunofluorescence, persisting for several weeks.
Takeo Miyamae (1974) conducted an observational in Avian encephalomyelitis. Avian encephalomyelitis virus infection was evaluated on Presence of viral antigens in the central nervous system. Viral antigens of avian encephalomyelitis were detected by immunofluorescence in the central nervous systems of 5-to-40-day-old chickens from outbreaks, persisting for at least 11-36 days.
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