Improvement in Psychosocial Functioning During an Intensive Cardiovascular Lifestyle Modification Program

In Brief PURPOSE Psychosocial factors have significant effects on development and progression of coronary artery disease (CAD), but appropriate strategies for clinical management of multiple risk factors in persons with CAD are not well defined. This study evaluated changes in psychosocial functioning in patients with cardiovascular disease participating in an intensive lifestyle modification program. Methods One hundred seventy-six patients participated in a prospective, nonrandomized intervention designed to stabilize or reverse progression of CAD through dietary changes, exercise, stress management, and group support. Three examinations over the course of 1 year assessed psychosocial functioning, physiological and biochemical CAD risk factors, and risk for future coronary events. Results Most patients showed significant improvements in mental health and quality of life as well as significant reductions in traditional CAD risk factors and cardiovascular risk. The intervention was effective in producing clinically meaningful changes in psychosocial functioning. Response rates were approximately 90% for clinical depression, 85% for stress, and 87% for mental health. Conclusions A comprehensive lifestyle intervention can reduce multiple psychometric risk factors and produce clinically relevant improvement in measures of depression, stress, and mental health. Cardiac rehabilitation programs that effectively address psychosocial and physiological outcomes may be valuable alternatives or supplements to pharmacologic treatments for reducing multiple psychosocial risk factors for CAD. Patients in a lifestyle change intervention designed to stabilize or reverse progression of coronary artery disease showed clinically relevant changes in psychosocial functioning. Lifestyle modification may be an effective alternative to pharmacologic treatments for reducing psychosocial risk factors in cardiac rehabilitation programs.