Why the study?
Does remifentanil improve intra-operative hemodynamic stability compared to alfentanil in patients undergoing major abdominal surgery?
Does remifentanil improve intra-operative hemodynamic stability compared to alfentanil in patients undergoing major abdominal surgery?
Remifentanil offers superior intra-operative hemodynamic stability during stressful surgical events compared with alfentanil, but requires careful postoperative titration to avoid respiratory depression and muscle rigidity.
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Remifentanil may be preferred over alfentanil for intraoperative hemodynamic stability in major abdominal surgery; extends RCT evidence on opioid selection.
Schüttler et al. (1997) studied this question.
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