Why the study?
Hypertension causes renal and cardiovascular disease, and early identification of glomerular injury could enable preventive measures against cardiovascular events. The authors evaluated whether nephrin can detect early glomerular injury in treatment-naïve hypertensive subjects.
Can urine nephrin serve as a biomarker of early glomerular injury in newly diagnosed, untreated hypertensive subjects?
Can urine nephrin serve as a biomarker of early glomerular injury in newly diagnosed, untreated hypertensive subjects?
Urine nephrin may serve as an early biomarker of glomerular injury in hypertensive patients prior to the development of microalbuminuria.
No takes yet. Share an insight, caveat, or question.
Nephrin may flag early glomerular injury in untreated hypertension; hypothesis-generating and requires validation before any clinical role.
Devanath et al. (2022) studied this question.
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