Why the study?
Does a PCR-based seroneutralization assay improve the diagnosis of hepatitis E compared to ELISA?
Population
Sera from healthy individuals and patients with hepatitis living in France, monkeys, patients during an…
Comparison
PCR-based seroneutralization assay in cell culture vs Available enzyme-linked immunosorbent assay
Design
Other
Authors
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May support hepatitis E confirmation in outbreaks; leaves open superiority to ELISA pending comparative validation.
Does a PCR-based seroneutralization assay improve the diagnosis of hepatitis E compared to ELISA?
A new PCR-based seroneutralization assay offers a potential confirmatory test for hepatitis E, addressing false-positive and false-negative issues with current ELISA methods.
Meng et al. (1997) studied this question.
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