TQ-ST changes on AC coupled ECG are unreliable for evaluating drug effects on ischemic myocardium in a porcine model.
AC-coupled TQ-ST should not inform clinical ischemia assessment or drug evaluation; leaves open development of reliable human indices.
.TQ-ST changes recorded by AC coupled ECG are not a reliable index of ischemia and therefore cannot be used to evaluate the effects of drugs that might affect the electrophysiologic properties of ischemic myocardium.
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Watanabe et al. (2017) studied this question.
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