What does this research mean for the field?

Precordial and epicardial ECG TQ and ST segment deflections are complex functions of ischemic geometry, where precordial ST elevation is directly related and epicardial ST elevation is inversely related to ischemic size, making simple interpretations of ischemic size from these deflections potentially misleading. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

October 1, 1975Circulation ResearchOpen Access

Precordial and epicardial surface potentials during Myocardial ischemia in the pig. A theoretical and experimental analysis of the TQ and ST segments.

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Why the study?

How do precordial and epicardial TQ and ST segment deflections relate to the size, shape, and transmural location of myocardial ischemia in a pig model?

Population

Anesthetized closed-chest pigs

Design

Preclinical

Authors

RHRoger P. HollandUnited States Department of the Army HBH. L. BrooksEvotec (United States)

Discussion

Member takes

Implication

Urges caution in ECG-based ischemic size estimates; leaves open human translation of lead-specific ST relationships.

Structured PICO

How do precordial and epicardial TQ and ST segment deflections relate to the size, shape, and transmural location of myocardial ischemia in a pig model?

Population

Anesthetized closed-chest pigs

Intervention

Myocardial ischemia produced by occluding large and small coronary artery branches

Outcome

TQ and ST segment deflections recorded from precordial and epicardial locationssurrogate

Precordial and epicardial ECG TQ and ST segment deflections are complex functions of ischemic geometry, making their interpretation regarding ischemic size and shape difficult.

Cite This Study

Holland et al. (1975) studied this question.

synapsesocial.com/papers/6a14c2ca2f0e848eb39ac866 https://doi.org/10.1161/01.res.37.4.471

View Full Paper

Ask AI

Bookmark

October 1, 1975Circulation ResearchOpen Access

Precordial and epicardial surface potentials during Myocardial ischemia in the pig. A theoretical and experimental analysis of the TQ and ST segments.

View Full Paper

Ask AI

Bookmark

Why the study?

How do precordial and epicardial TQ and ST segment deflections relate to the size, shape, and transmural location of myocardial ischemia in a pig model?

Population

Anesthetized closed-chest pigs

Design

Preclinical

Authors

RHRoger P. HollandUnited States Department of the Army HBH. L. BrooksEvotec (United States)

Discussion

Member takes

Implication

Urges caution in ECG-based ischemic size estimates; leaves open human translation of lead-specific ST relationships.

Structured PICO

How do precordial and epicardial TQ and ST segment deflections relate to the size, shape, and transmural location of myocardial ischemia in a pig model?

Population

Anesthetized closed-chest pigs

Intervention

Myocardial ischemia produced by occluding large and small coronary artery branches

Outcome

TQ and ST segment deflections recorded from precordial and epicardial locationssurrogate

Precordial and epicardial ECG TQ and ST segment deflections are complex functions of ischemic geometry, making their interpretation regarding ischemic size and shape difficult.

Cite This Study

Holland et al. (1975) studied this question.

synapsesocial.com/papers/6a14c2ca2f0e848eb39ac866 https://doi.org/10.1161/01.res.37.4.471

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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