Population
3D computer model of a real dog heart discretized into 1473 interconnected cubic elements
Design
Preclinical
Authors
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Hypothesis-generating for refractory dispersion in fibrillation; leaves open translation to human arrhythmia management.
This 3D computer model demonstrates that dispersion of refractory states can cause fibrillation following extrastimulation.
Thakor et al. (1989) studied this question.
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