The L. E. Phenomenon in Rheumatoid Arthritis

Article1 June 1957THE L. E. PHENOMENON IN RHEUMATOID ARTHRITISIRVING A. FRIEDMAN, M.D., JEROME F. SICKLEY, M.D., ROBERT M. POSKE, M.D., ARNOLD BLACK, M.D., DAVID BRONSKY, M.D., WILSON H. HARTZ JR., M.D., CHARLOTTE FELDHAKE, B.S., PAUL S. REEDER, M.D., ELI M. KATZ, M.D.IRVING A. FRIEDMAN, M.D.Search for more papers by this author, JEROME F. SICKLEY, M.D.Search for more papers by this author, ROBERT M. POSKE, M.D.Search for more papers by this author, ARNOLD BLACK, M.D.Search for more papers by this author, DAVID BRONSKY, M.D.Search for more papers by this author, WILSON H. HARTZ JR., M.D.Search for more papers by this author, CHARLOTTE FELDHAKE, B.S.Search for more papers by this author, PAUL S. REEDER, M.D.Search for more papers by this author, ELI M. KATZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-6-1113 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe specificity of the lupus erythematosus phenomenon for the diagnosis of systemic lupus erythematosus has been emphasized by many investigators.1, 7Nevertheless, occasional reports continue to appear describing this phenomenon in diseases other than systemic lupus erythematosus. Positive reactions have been reported in isolated cases of periarteritis nodosa,8thrombotic thrombocytopenic purpura,9tuberculosis10, 11and postnecrotic cirrhosis.12, 13The phenomenon has been reported after hypersensitivity reactions to penicillin,14, 15tetanus antitoxin,16phenylbutazone17and following the administration of hydralazine18, 19, 20and prolonged steroid therapy.21, 22The presence of L. 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Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication November 15, 1956.From the Hematology Laboratory and the Hektoen Institute for Medical Research of the Cook County Hospital, Chicago, Illinois; The Oak Forest Institutions, Oak Forest, Illinois; Department of Medicine, U. S. Veterans Administration Hospital, Hines, Illinois; Chicago Medical School, Chicago, Illinois; University of Illinois College of Medicine, Chicago, Illinois, and Northwestern University Medical School, Chicago, Illinois.Aided by grants from the Olivia Sue Dvore, Edward Friedman and Benjamin fishbain Foundations.Presented at the Midwest Regional Meeting of the American College of Physicians, October 15, 1955.†Jerome D. Solomon Postdoctorate Research Fellow in Hematology.Requests for reprints should be addressed to Irving A. Friedman, M.D., Associate Director, Hematology Laboratory, The Hektoen Institute for Medical Research of the Cook County Hospital, 637 South Wood Street, Chicago 12, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Kidney Function in Relation to Drug Consumption in Patients with Rheumatoid Arthritis. 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FRIEDMAN, M.D., SAMUEL KESSLER, M.D., STEVEN O. SCHWARTZ, M.D., F.A.C.P. 1 June 1957Volume 46, Issue 6Page: 1113-1136KeywordsArthritisHematology and oncologyHospital medicineLupus erythematosusRheumatoid arthritisSpecificitySpondylitisSteroid therapySystemic lupus erythematosusTetanus ePublished: 1 December 2008 Issue Published: 1 June 1957 PDF downloadLoading ...