February 1, 2000Fisheries ScienceOpen Access

Filament formation of carboxyl- and amino-group-modified carp myosin rod

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Population

Carp myosin rod

Comparison

Chemical modification of carboxyl groups and… vs Unmodified myosin rod

Design

Preclinical

Authors

Discussion

Hypothesis-generating for myosin assembly; extends basic filament insights but leaves open cardiac translation.

Population

Carp myosin rod

Intervention

Chemical modification of carboxyl groups (carbodiimide-mediated amidation using glycine ethyl ether) and amino groups (using sodium formate)

Comparator

Unmodified myosin rod

Outcome

Filament formation (self-assembly)surrogate

Surface negative charges of the carp myosin rod play an important role in its filament formation.

Kato et al. (2000) studied this question.

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