Why the study?
Does aerobic exercise pretreatment reduce doxorubicin-induced histological heart tissue damage in young and old rats?
Population
48 male rats, divided into young and old age groups
Comparison
Pretreatment with 3 weeks of aerobic exercise… vs Doxorubicin alone, and control
Design
Preclinical
Follow-up
48 hours after doxorubicin injection
Authors
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Three weeks of aerobic exercise pretreatment reduces doxorubicin-induced cardiac tissue damage (edema and apoptosis) in a rat model, particularly in older animals.
Does aerobic exercise pretreatment reduce doxorubicin-induced histological heart tissue damage in young and old rats?
Three weeks of aerobic exercise pretreatment reduces doxorubicin-induced cardiac tissue damage (edema and apoptosis) in a rat model, particularly in older animals.
Azizi et al. (2018) studied this question.
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