What question did this study set out to answer?

To evaluate the safety, efficacy, and patient-reported outcomes of ambulatory shock delivery using an implantable atrial defibrillator in patients with recurrent atrial fibrillation.

September 19, 2000CirculationOpen Access

Initial Clinical Experience With Ambulatory Use of an Implantable Atrial Defibrillator for Conversion of Atrial Fibrillation

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Why the study?

Does ambulatory use of an implantable atrial defibrillator safely and effectively convert atrial fibrillation in patients with recurrent, symptomatic, drug-refractory atrial fibrillation?

Population

105 patients with recurrent, symptomatic, drug-refractory atrial fibrillation

Design

Cohort

Follow-up

mean 11.7 months

Authors

EDEmile G. DaoudElectrophysiology CTCarl TimmermansMaastricht University Medical Centre CFChris FellowsVirginia Mason Medical Center

Discussion

Member takes

Implication

May support ambulatory atrial defibrillation in refractory AF; hypothesis-generating and should not yet change practice.

Key Points

To evaluate the safety, efficacy, and patient-reported outcomes of ambulatory shock delivery using an implantable atrial defibrillator in patients with recurrent atrial fibrillation.
Enrolled 105 patients (mean age 59±12 years; 75 men) with recurrent, drug-refractory atrial fibrillation undergoing defibrillator implantation.
Following a successful 3-month testing phase, 48 eligible patients transitioned to ambulatory shock delivery over a mean follow-up of 11.7 months, treating 275 total episodes.
Evaluated shock discomfort and overall therapy satisfaction after each treated episode using a 10-point visual-analog scale.
Overall shock therapy efficacy was 90%, requiring a mean of 1.6±1.2 shocks per episode (median, 1 shock).
Shock discomfort was rated 5.2±2.4 for successful versus 4.2±2.2 for unsuccessful episodes (P > 0.05), with significantly higher satisfaction reported for successful conversion (P < 0.05).
No episodes of ventricular proarrhythmia were observed throughout the 11.7-month mean follow-up.

Structured PICO

Does ambulatory use of an implantable atrial defibrillator safely and effectively convert atrial fibrillation in patients with recurrent, symptomatic, drug-refractory atrial fibrillation?

Population

105 patients (75 men; mean age, 59+/-12 years) with recurrent, symptomatic, drug-refractory atrial fibrillation

Intervention

Ambulatory use of an implantable atrial defibrillator

Outcome

Safety and efficacy of ambulatory use (shock therapy efficacy, shock discomfort, and therapy satisfaction using a 10-point visual-analog scale)patient reported

Ambulatory use of an implantable atrial defibrillator is safe, highly effective (90% conversion rate), and associated with high patient satisfaction for treating recurrent atrial fibrillation.

Cite This Study

Daoud et al. (2000) studied this question.

synapsesocial.com/papers/6a8d0742de501e4dcdd4f910 https://doi.org/10.1161/01.cir.102.12.1407

Topics

Atrial fibrillation Persistent AF management Cardiac device therapy AF ablation outcomes Anticoagulation in AF

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Initial Clinical Experience With Ambulatory Use of an Implantable Atrial Defibrillator for Conversion of Atrial Fibrillation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Initial Clinical Experience With Ambulatory Use of an Implantable Atrial Defibrillator for Conversion of Atrial Fibrillation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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