Why the study?
Does measuring IGF-II, IGFBP-2, and ALS improve the detection of rhIGF-I/rhIGFBP-3 administration in recreational athletes?
Population
56 recreational athletes (26 female, 30 male)
Comparison
Recombinant humanIGF-I/rhIGF binding protein-3… vs Placebo for 28 days
Design
RCT, randomized
Follow-up
84 days (28 days treatment, 56 days washout)
Authors
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Supports refining anti-doping protocols for rhIGF-I abuse; extends biomarker panels for improved sensitivity in athletes.
Does measuring IGF-II, IGFBP-2, and ALS improve the detection of rhIGF-I/rhIGFBP-3 administration in recreational athletes?
Combining IGF-I with IGF-II and/or IGFBP-2 improves the detection of rhIGF-I/rhIGFBP-3 doping in athletes.
Holt et al. (2016) studied this question.
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