Comparison of results and age-related changes in establishing reference intervals for CEA, AFP, CA125, and CA199 using four indirect methods

Figures

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  Fig. 1. Comparison of RIs established using four indirect methods *M, male; F, female; and NPM, non-parametric method. Different colors represent different algorithms, the points on the line represent the reference interval values of the corresponding groups, The horizontal lines at both ends of this point represent the 90 % CIs of this point. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

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  Fig. 2. Comparison of four algorithms validation pass rates in males and females *M, male; F, female; and NPM, non-parametric method,the position of each point on the chart represents the group's pass rate. A red dashed line is utilized as the 90 % pass threshold. The pass rate to the left of the red line ranges from 0.8 to 0.9, while the pass rate to the right of the red line ranges from 0.9 to 1.0. The black dot located to the left of the red dashed line represents the verification failure point, while the point located to the right of the dashed line represents the verification pass point. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)