April 1, 1988Circulation
Immediate enhancement of left ventricular relaxation by coronary artery bypass grafting: intraoperative assessment.
Why the study?
Does coronary artery bypass grafting improve left ventricular relaxation in patients with coronary artery disease?
Population
18 patients undergoing open heart surgery, including 12 with coronary artery disease and 6 without coronary…
Comparison
Coronary artery bypass grafting (CABG) vs Cardiopulmonary bypass during other open heart…
Design
Cohort
Follow-up
Intraoperative (immediately after bypass)
Authors
Discussion
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Member takes
Implication
CABG may acutely improve LV relaxation in CAD; leaves open causal effects on outcomes pending randomized confirmation.
Structured PICO
Does coronary artery bypass grafting improve left ventricular relaxation in patients with coronary artery disease?
P
Population
18 patients undergoing open heart surgery, including 12 with coronary artery disease and 6 without coronary artery disease (controls).
I
Intervention
Coronary artery bypass grafting (CABG)
C
Comparator
Cardiopulmonary bypass during other open heart procedures (in control patients without CAD)
O
Outcome
Rate of left ventricular relaxation (time constant for isovolumetric relaxation, T, in milliseconds)surrogate
Coronary artery bypass grafting immediately enhances left ventricular relaxation, likely due to the relief of myocardial ischemia.
Cite This Study
Humphrey et al. (1988) studied this question.