Why the study?
Do psychosocial stimuli increase plasma renin activity in unanesthetized rats?
Population
Unanesthetized rats maintained on either a standard (1% NaCl) or sodium-free diet
Design
Preclinical
Follow-up
30 minutes
Authors
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Sympathetic mediation of stress-induced renin release in rats is supported; leaves open translation to human cardiovascular disease.
Do psychosocial stimuli increase plasma renin activity in unanesthetized rats?
Psychosocial stress significantly increases plasma renin activity in rats, a response that is partially mediated by the sympathetic nervous system.
Clamage et al. (1976) studied this question.
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