Why the study?
Does the presence of frailty predict adverse cardiac events in patients with congestive heart failure?
Does the presence of frailty predict adverse cardiac events in patients with congestive heart failure?
Objective frailty criteria including weakness, exhaustion, and slowness can serve as a significant risk marker for predicting adverse cardiac events in patients with congestive heart failure.
Frailty criteria may stratify cardiac event risk in CHF; leaves open whether interventions targeting frailty improve outcomes.
AIMS: To examine the availability of frailty concept with objective criteria for risk stratification in patients with congestive heart failure (CHF). METHODS AND RESULTS: Study design was secondary analysis of our CHF cohort. We selected 181 patients who completed clinical assessments and were successfully followed 2-year post discharge. To set frailty criteria, grip strength <26 kg in men and <17 kg in women (weakness) and performance measure for activities of daily living-8 ≧21 points (exhaustion) were defined for predicting 6 min walking distance <300 m (slowness) by the receiver-operating characteristics. During 2 years of follow up, subjects who met all the criteria had a 4 times greater risk of cardiac event compared with those with no frailty criteria. CONCLUSION: The findings of present study suggest that frailty criteria may serve as a new clinical marker for management of patients with CHF.
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Yamada et al. (2015) studied this question.
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