Why the study?
Cytokines play a pivotal role in heart failure pathophysiology, and understanding their role could provide precise grounds for early diagnosis, therapy, and prognosis.
Population
116 participants
Comparison
Heart failure group (n = 59) vs age- and gender-matched healthy control group (n = 57)
Design
Case-control study
Authors
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Suggests cytokine profiling remains hypothesis-generating for heart failure prognostication; leaves.
Multiple inflammatory cytokines, particularly IL-6, IL-8, and IL-17, are independently associated with heart failure and offer high diagnostic value when combined, though NT-proBNP remains the preferred clinical biomarker.
Yu et al. (2023) studied this question.
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