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January 1, 2023JOURNAL OF CARDIO-VASCULAR-THORACIC ANAESTHESIA AND INTENSIVE CARE SOCIETYOpen Access

A preoperative SII cutoff of 651.7 predicted AKI with 65.0% sensitivity, 64.9% specificity, and an AUC of 0.718 (95% CI 0.676-0.760).

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Why the study?

Inflammation plays an essential role in postoperative AKI, and the predictive value of the systemic immune-inflammation index (SII) for AKI following CABG needed to be examined.

Does the preoperative systemic immune-inflammation index (SII) predict acute kidney injury following coronary artery bypass grafting?

Population

Patients who received CABG operation in 2022 classified into AKI (n=160) and non-AKI groups (n=424)

Comparison

Patients with AKI vs non-AKI

Design

Retrospective observational study

Follow-up

7 days postsurgery

Authors

EZEmine Nilgün Zengin

Discussion

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Member takes

Overview

The systemic immune-inflammation index is a useful preoperative biomarker for predicting the risk of acute kidney injury after CABG surgery.

Structured PICO

Does the preoperative systemic immune-inflammation index (SII) predict acute kidney injury following coronary artery bypass grafting?

P
Population
584 patients who received coronary artery bypass grafting (CABG) operation in 2022 (160 with AKI, 424 without AKI).
I
Intervention
Preoperative systemic immune-inflammation index (SII)
O
Outcome
Incidence of acute kidney injury (AKI) 7 days postsurgery using Kidney Disease Improving Global Outcomes (KDIGO) criteriahard clinical

The systemic immune-inflammation index is a useful preoperative biomarker for predicting the risk of acute kidney injury after CABG surgery.

Cite This Study

Emine Nilgün Zengin (2023) studied this question.

synapsesocial.com/papers/6a8d2313d881876296cf8aaahttps://doi.org/10.14744/gkdad.2023.79664
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Systemic Immune-Inflammation Index (SII) as a Predictor of Short-Term Mortality Risk in Sepsis-Associated Acute Kidney Injury: A Retrospective Cohort Study2024 · 5 citations
  2. 2Systemic inflammatory response index is associated with acute kidney injury following cardiac surgery: A retrospective cohort study using the MIMIC database2026 · 2 citations
  3. 3The Systemic Immune-Inflammation Index Predicts In-Hospital Mortality in Patients Who Underwent On-Pump Cardiac Surgery2024 · 7 citations
  4. 4Inflammatory Biomarkers Predicting Contrast-Induced Acute Kidney Injury in Elderly Patients with ST-Segment Elevation Myocardial Infarction2025 · 4 citations
  5. 5Preoperative systemic immune inflammation index predicts early complications and 30-day mortality after heart valve surgery: a retrospective cohort study2026