Population
1 77-year-old woman with allergic skin disease, taking cimetidine, and diagnosed with vasospastic angina
Design
Case_report
Follow-up
6 months
Authors
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May warrant avoiding astemizole with CYP inhibitors; single case leaves interaction risks open for confirmation.
This case highlights the risk of QT prolongation and torsades de pointes when astemizole is co-administered with cytochrome P-450 inhibitors like cimetidine.
Ikeda et al. (1998) studied this question.
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