Key result
Impaired activities of daily living at hospital admission was an independent risk factor for periprocedural myocardial infarction (OR 1.190) following percutaneous coronary intervention.
Why the study?
There is growing interest in exploring the relationship between activities of daily living and cardiovascular diseases, but its association with periprocedural myocardial infarction and injury following PCI required investigation.
Does impaired ADL at admission predict periprocedural myocardial infarction and injury in patients undergoing PCI?
Cross-Sectional (n=11,028)
Yes
Does impaired ADL at admission predict periprocedural myocardial infarction and injury in patients undergoing PCI?
Odds Ratio: 1.19 (95% CI 1.041–1.36)
p-value: p=0.011
Impaired activities of daily living at hospital admission is an independent predictor of periprocedural myocardial infarction and injury in patients undergoing percutaneous coronary intervention.
Suggests baseline functional status may predict periprocedural myocardial infarction risk during PCI; leaves open whether.
Background In recent years, there has been growing interest in exploring the relationship between activities of daily living (ADL) and cardiovascular diseases. This retrospective cross-sectional study aimed to investigate the association of ADL measured by Barthel index (BI) with periprocedural myocardial infarction (PMI) and injury following percutaneous coronary intervention (PCI). Methods Enrolled patients were stratified into impaired and unimpaired ADL groups according to their BI scores. Logistic regressions were conducted to explore the association of ADL on admission with periprocedural myocardial injury and infarction. Restricted cubic spline (RCS) curve and subgroup analysis were also performed. Results Totally, 16.4% of patients suffered from PMI; the mean age was 65.8 ± 10.4 years old. RCS analysis showed that the morbidity of periprocedural myocardial infarction and injury showed a downward tendency with increasing BI scores. Multivariable logistic regression analysis demonstrated that impaired ADL was an independent risk factor for periprocedural myocardial infarction (OR = 1.190, 95% CI [1.041, 1.360], P = 0.011) and injury (OR = 1.131, 95% CI [1.017, 1.257], P = 0.023). Subgroup analysis showed that the association between ADL and PMI was founded in several subgroups, while the association between ADL and periprocedural myocardial injury was founded only in BMI ≥ 24 kg/m2 subgroup. Conclusion Impaired ADL at hospital admission was an independent risk factor for periprocedural myocardial infarction and injury among patients following PCI.
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Pan et al. (2023) conducted a cross-sectional in Coronary artery disease undergoing percutaneous coronary intervention (n=11,028). Impaired activities of daily living (Barthel index < 100) vs. Unimpaired activities of daily living (Barthel index = 100) was evaluated on Periprocedural myocardial infarction (OR 1.190, 95% CI 1.041, 1.360, p=0.011). Impaired activities of daily living at hospital admission was an independent risk factor for periprocedural myocardial infarction (OR 1.190) following percutaneous coronary intervention.
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