Key result
Among 164 young children hospitalized with acute gastroenteritis of unknown etiology, Saffold virus was detected in 0.6% (1 case) and Human Cosavirus was not detected in any samples.
Why the study?
Human Cosavirus and Saffold virus have a worldwide distribution and have been detected in acute gastroenteritis, but more insights were needed into the epidemiology of enteric viruses not routinely tested.
What is the prevalence of human Cosavirus and Saffold virus in young children hospitalized with gastroenteritis of unknown etiology in Northern Italy?
Cross-Sectional (n=164)
No
What is the prevalence of human Cosavirus and Saffold virus in young children hospitalized with gastroenteritis of unknown etiology in Northern Italy?
HCoSV and SAFV are rare causes of childhood sporadic gastroenteritis requiring hospital admission in Northern Italy.
These viruses are exceptionally rare contributors to severe pediatric gastroenteritis; leaves open whether routine screening for.
BACKGROUND: Gastroenteritis is a common disease in children, characterized by diarrhea, vomiting, abdominal pain, and fever. Human Cosavirus (HCoSV) and Saffold virus (SAFV) both have a worldwide distribution. Both viruses have been detected in the stools of patients with acute gastroenteritis in several countries.METHODS: In order to provide more insights into the epidemiology of enteric viruses that are not included usually in routine diagnostic tests, cases of childhood sporadic gastroenteritis of unknown etiology requiring hospital admission in Turin, Italy, during December 2014 to November 2015, were screened for HCoSV and SAFV.RESULTS: A total of 1 out of 164 (0.6%) episodes of acute gastroenteritis were associated with SAFV genomic detection. Among the 1 SAFV-positive cases, 1 were also positive for Adenovirus. The patient positive for SAFV do not present diarrheal episodes but vomiting. HCoSV was not detected in any of the samples.CONCLUSIONS: In conclusion, this study presents the current epidemiological data regarding the two viruses, HCoSV and SAFV, circulating in pediatric patients admitted to hospital with acute gastroenteritis in Turin, Italy.
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Daprà et al. (2023) conducted a cross-sectional in childhood sporadic gastroenteritis of unknown etiology (n=164). Human Cosavirus (HCoSV) and Saffold virus (SAFV) screening was evaluated on SAFV and HCoSV genomic detection. Among 164 young children hospitalized with acute gastroenteritis of unknown etiology, Saffold virus was detected in 0.6% (1 case) and Human Cosavirus was not detected in any samples.
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