Saffold cardiovirus was detected in 3.2% (12 of 373) of children with acute gastroenteritis in Beijing, China, with most cases involving co-infection with other enteric viruses.
Observational (n=373)
No
Saffold cardiovirus (SAFV-1 sublineage) is present in a small percentage of children with acute gastroenteritis in China, though its clinical role remains unclear due to frequent co-infections.
To understand Saffold cardiovirus (SAFV) distribution, prevalence, and clinical relevance in China, we retrospectively studied SAFV in children with acute gastroenteritis and found SAFV in 12 (3.2%) of 373. Sequence homology of virus protein 1 genes suggested these strains belong to the SAFV-1 sublineage. SAFVs were found in samples positive for other diarrhea-causing viruses.
Ren et al. (2009) conducted an observational in Acute gastroenteritis (n=373). Saffold cardiovirus was detected in 3.2% (12 of 373) of children with acute gastroenteritis in Beijing, China, with most cases involving co-infection with other enteric viruses.