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October 1, 1988Pediatrics International

Doppler echocardiography demonstrated significant alterations in ventricular hemodynamics in TOF patients before surgery compared to post-surgery and controls, and a new method for estimating Qp/Qs correlated well with the Fick method.

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Why the study?

Can Doppler echocardiography accurately evaluate hemodynamic changes in patients with tetralogy of Fallot before and after corrective surgery compared to healthy controls?

Population

61 patients with tetralogy of Fallot and 118 healthy children

Comparison

Two-dimensional Doppler echocardiography vs Pre-corrective surgery vs post-corrective…

Design

Cohort

Key result

Doppler echocardiography demonstrated significant alterations in ventricular hemodynamics in TOF patients before surgery compared to post-surgery and controls, and a new method for estimating Qp/Qs correlated well with the Fick method.

Authors

TWTohoru WatariSAShoichi AwaTHToshio Hishi

Discussion

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Member takes

Overview

Supports Doppler assessment of TOF hemodynamics; hypothesis-generating and should not yet change practice.

Study Design

Type

Observational (n=179)

Multicenter

Yes

Structured PICO

Can Doppler echocardiography accurately evaluate hemodynamic changes in patients with tetralogy of Fallot before and after corrective surgery compared to healthy controls?

P
Population
179 children, comprising 61 with tetralogy of Fallot and 118 healthy controls, evaluated for hemodynamic changes pre- and post-corrective surgery using Doppler echocardiography.
E
Exposure
Two-dimensional Doppler echocardiography
C
Comparator
Pre-corrective surgery vs post-corrective surgery vs healthy controls
O
Outcome
Hemodynamic parameters including right ventricular systolic time intervals, peak velocities of ventricular filling and atrial contraction, and Qp/Qs ratiosurrogate

Doppler echocardiography is a useful non-invasive tool for evaluating hemodynamic changes and estimating Qp/Qs in patients with tetralogy of Fallot before and after corrective surgery.

Cite This Study

Watari et al. (1988) conducted an observational in Tetralogy of Fallot (n=179). Pre-corrective surgery state vs. Post-corrective surgery and healthy controls was evaluated on Hemodynamic parameters measured by Doppler echocardiography. Doppler echocardiography demonstrated significant alterations in ventricular hemodynamics in TOF patients before surgery compared to post-surgery and controls, and a new method for estimating Qp/Qs correlated well with the Fick method.

synapsesocial.com/papers/6a8da388e027b4651e7dd1c1https://doi.org/10.1111/j.1442-200x.1988.tb01582.x
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