Key result
Obesity in children was associated with significantly higher circulating levels of vascular endothelial cell and platelet activation markers compared to nonobese children (P < 0.0001).
Why the study?
Are markers of vascular endothelial cell and platelet activation elevated in obese children compared to nonobese children?
Case-Control (n=80)
Are markers of vascular endothelial cell and platelet activation elevated in obese children compared to nonobese children?
p-value: p=< 0.0001
Obese children already exhibit early activation of vascular endothelial cells and platelets, along with increased lipid peroxidation, suggesting a proinflammatory phenotype early in life.
No takes yet. Share an insight, caveat, or question.
May indicate early vascular activation in obese children; leaves open whether markers predict future events.
Desideri et al. (2005) conducted a case-control in Obesity (n=80). Obesity vs. Nonobese was evaluated on Circulating levels of vascular endothelial cell and platelet activation markers (p=< 0.0001). Obesity in children was associated with significantly higher circulating levels of vascular endothelial cell and platelet activation markers compared to nonobese children (P < 0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: