Key result
Antiserum to CD59 specifically blocked infection of rhabdomyosarcoma cells by a range of echoviruses prior to 'A' particle formation.
Antiserum to CD59 blocks echovirus infection in rhabdomyosarcoma cells, suggesting CD59 may play a role in the virus-receptor complex.
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CD59 may mediate echovirus entry; leaves open in vivo validation and antiviral targeting.
Goodfellow et al. (2000) studied Echovirus infection. Antiserum to CD59 was evaluated on Echovirus infection of rhabdomyosarcoma cells. Antiserum to CD59 specifically blocked infection of rhabdomyosarcoma cells by a range of echoviruses prior to 'A' particle formation.
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