Key result
Compared with controls, patients with PAH had significantly elevated T1 in the RV insertion (P=0.015), and both AS and PAH groups showed increased T2 in the RV insertion (P=0.01).
Why the study?
Does native T1 and T2 mapping by CMR detect differences in myocardial tissue characteristics in pressure overloaded left and right heart diseases?
Cross-Sectional (n=42)
Does native T1 and T2 mapping by CMR detect differences in myocardial tissue characteristics in pressure overloaded left and right heart diseases?
p-value: p=0.015
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Native T1 and T2 mapping by CMR can detect distinct patterns of myocardial tissue alteration in pressure overloaded left and right heart diseases, correlating with structural and functional remodeling.
Wang et al. (2018) conducted a cross-sectional in Pulmonary arterial hypertension and severe aortic valve stenosis (n=42). Pressure overload (PAH or severe AS) vs. Healthy volunteers was evaluated on Native T1 and T2 relaxation times in myocardial segments (p=0.015). Compared with controls, patients with PAH had significantly elevated T1 in the RV insertion (P=0.015), and both AS and PAH groups showed increased T2 in the RV insertion (P=0.01).
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