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High-grade gliomas are aggressive brain tumours with a poor prognosis. The current goal of treatment is to achieve maximum safe surgical resection as this improves survival. However, the infiltrative nature of this cancer makes it difficult to delineate healthy from pathological tissue. Therefore, complete resection is rarely achieved and there is a high rate of tumour recurrence. Additionally, misdiagnosis is common and results from unrepresentative tissue sampling. This can lead to the initiation of incorrect adjuvant therapies.
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Suresh Vishnu A (2023) studied this question.
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