Key result
Higher preoperative anaerobic threshold was independently associated with a reduced risk of major postoperative complications after radical cystectomy (OR 0.74; 95% CI 0.57-0.97; P=0.03).
Why the study?
Does preoperative cardiopulmonary reserve predict postoperative morbidity and length of hospital stay in elderly patients undergoing radical cystectomy?
Population
82 consecutive elderly patients planned to undergo radical cystectomy (69 analyzed after exclusions)
Design
Cohort, Results of CPET were blinded from clinicians involved in patient care
Follow-up
Postoperative period
Authors
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May inform preoperative risk stratification before radical cystectomy; leaves open whether targeting anaerobic threshold improves outcomes.
Cohort (n=69)
Clinicians blinded to CPET results
Does preoperative cardiopulmonary reserve predict postoperative morbidity and length of hospital stay in elderly patients undergoing radical cystectomy?
Odds Ratio: 0.74 (95% CI 0.57–0.97)
p-value: p=0.03
Impaired preoperative cardiopulmonary reserve (anaerobic threshold <12 mL/min/kg) predicts major morbidity and prolonged hospital stay after radical cystectomy.
Prentis et al. (2013) conducted a cohort in Radical cystectomy (n=69). Preoperative cardiopulmonary reserve (anaerobic threshold) vs. Lower anaerobic threshold was evaluated on Major postoperative complications (OR 0.74, 95% CI 0.57-0.97, p=0.03). Higher preoperative anaerobic threshold was independently associated with a reduced risk of major postoperative complications after radical cystectomy (OR 0.74; 95% CI 0.57-0.97; P=0.03).
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