Key result
Serum uric acid was positively associated with the atherogenic index of plasma (r = 0.2, p < 0.01), suggesting its utility as a supplementary marker for atherosclerosis in upper-middle-aged men.
Observational (n=248)
Effect estimate: r = 0.2
p-value: p=<0.01
Serum uric acid is positively associated with the atherogenic index of plasma and may serve as a supplementary marker for atherosclerosis risk in upper-middle-aged men.
Extends observational links to atherogenic index; leaves open incremental value for risk stratification in men.
CONTEXT: Serum uric acid (SUA) has been known to be associated with cardiovascular diseases. "Atherogenic index of plasma" (AIP) is considered a very sensitive predictor of future cardiovascular events. OBJECTIVES: This study was conducted to analyse the association of AIP with SUA and various other lipid parameters. METHODS: Parameters were measured on a fully automated analyser using standard reagent kits in a retrospective study involving 248 male Indian subjects between 40 to 59 years of age. RESULTS: AIP correlates: moderately with TC/HDL-C (r = 0.47, p < 0.0001); to a lesser extent but comparably (r = 0.2, p < 0.01) with SUA, LDL-C/HDL-C and TC; negligibly with LDL-C and age. DISCUSSION AND CONCLUSION: As SUA is positively associated with AIP it can be used as a supplementary marker for atherosclerosis/CVD in upper-middle-aged men.
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Baliarsingh et al. (2012) reported an observational. Serum uric acid was evaluated on Association of atherogenic index of plasma (AIP) with serum uric acid (SUA) (r = 0.2, p=<0.01). Serum uric acid was positively associated with the atherogenic index of plasma (r = 0.2, p < 0.01), suggesting its utility as a supplementary marker for atherosclerosis in upper-middle-aged men.
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