Key result
Among non-invasive tests for pulmonary embolism, d-dimer had the highest sensitivity (90%) and ECG showing S1Q3T3 had the highest specificity (100%) compared to MDCT pulmonary angiography.
Why the study?
Do non-invasive diagnostic tests accurately diagnose pulmonary embolism compared to MDCT pulmonary angiography in hospitalized patients with Wells score > 2?
Cohort (n=80)
Do non-invasive diagnostic tests accurately diagnose pulmonary embolism compared to MDCT pulmonary angiography in hospitalized patients with Wells score > 2?
MDCT pulmonary angiography remains the most accurate test for diagnosing PE, though a combination of 2D ECHO and d-dimer can be used when MDCT is not possible.
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May support non-invasive adjuncts when MDCT unavailable; hypothesis-generating and requires prospective validation before practice change.
Firdous et al. (2013) conducted a cohort in Acute pulmonary embolism (n=80). Non-invasive diagnostic tests vs. Multi-detector CT pulmonary angiography was evaluated on Diagnostic performance (sensitivity, specificity, PPV, NPV) for pulmonary embolism. Among non-invasive tests for pulmonary embolism, d-dimer had the highest sensitivity (90%) and ECG showing S1Q3T3 had the highest specificity (100%) compared to MDCT pulmonary angiography.
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