January 1, 2000Canadian Journal of Physiology and Pharmacology

Baroreceptors, α1-adrenergic receptors, and regulation of mesenteric blood flow

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Population

Rats anesthetized with isoflurane

Comparison

Sinoaortic denervation, mesenteric denervation… vs Central mechanisms intact (baseline)

Design

Preclinical

Authors

IAIsam Abu‐AmarahLoyola University Medical Center WCWilliam A. CupplesSimon Fraser University

Discussion

Member takes

Implication

Remains hypothesis-generating in rats; leaves open translation of admittance-based baroreflex assessment to human physiology.

Structured PICO

Population

Rats anesthetized with isoflurane

Intervention

Sinoaortic denervation, mesenteric denervation, and alpha1-adrenergic blockade

Comparator

Central mechanisms intact (baseline)

Outcome

Blood pressure and mesenteric blood flow (admittance phase and gain)surrogate

The baroreflex acting on the mesenteric circulation in rats can be identified by admittance phase, with part of the response mediated by alpha1-adrenergic transmission.

Cite This Study

Abu‐Amarah et al. (2000) studied this question.

synapsesocial.com/papers/6a8e6d8a7ed0ac3998fff002 https://doi.org/10.1139/cjpp-78-1-54

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Baroreceptors, α1-adrenergic receptors, and regulation of mesenteric blood flow

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Baroreceptors, α1-adrenergic receptors, and regulation of mesenteric blood flow

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider