Why the study?
What are the risks and outcomes of anticoagulation with vitamin K antagonists in pregnant women with metallic prosthetic heart valves?
Population
Pregnant women with metallic prosthetic heart valves
Comparison
Anticoagulation with vitamin K antagonists vs Inadequate anticoagulation or suspension of oral…
Design
Review
Follow-up
Pregnancy and postpartum period
Authors
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Persistent maternal risks warrant individualized counseling; leaves open optimal anticoagulation strategies for mechanical valves in pregnancy.
What are the risks and outcomes of anticoagulation with vitamin K antagonists in pregnant women with metallic prosthetic heart valves?
Managing pregnant women with metallic valve prostheses requires balancing the high risk of maternal valve thrombosis against the teratogenic and bleeding risks of vitamin K antagonists.
Seabra-Garcez et al. (2015) studied this question.
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