Population
Detergent-skinned porcine carotid artery and bovine aortic native actomyosin
Comparison
Aortic myosin light-chain phosphatase vs Absence of phosphatase or lower concentrations
Design
Preclinical
Authors
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Findings in isolated aortic tissue should not yet inform clinical practice; hypothesis-generating for myosin phosphatase regulation of vascular tone.
Myosin phosphatase modulates actin-myosin interactions in vascular smooth muscle by regulating myosin light-chain phosphorylation.
Bialojan et al. (1985) studied this question.
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