Why the study?
Does partial occlusion of the pulmonary artery increase pulmonary blood flow in anesthetized dogs?
Does partial occlusion of the pulmonary artery increase pulmonary blood flow in anesthetized dogs?
Partial occlusion of the pulmonary artery induces reflex cardiac stimulation and increased pulmonary blood flow mediated entirely by cardiac sympathetic nerves.
Hypothesis-generating in canine models; leaves open translation of sympathetic dependence to human pulmonary artery responses.
In anesthetized dogs, partial occlusion of the pulmonary artery causes increased pulmonary blood flow which is dependent on an intact sympathetic innervation of the heart. Neither the vagi nor the medullary centers participate in the increase in pulmonary blood flow. The most probable explanation is that the increase in pulmonary blood flow is due to reflex cardiac stimulation initiated by a rise in right ventricular systolic pressure and mediated entirely by the cardiac sympathetic nerves.
No takes yet. Share an insight, caveat, or question.
Taquini et al. (1961) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: