Why the study?
Does stimulation of pulmonary arterial baroreceptors evoke reflex cardiovascular and respiratory responses in anaesthetised dogs?
Population
Anaesthetised dogs with widely opened chests and cardiopulmonary bypass (n=13)
Comparison
Increases in pulmonary arterial pressure vs Baseline or lower levels of pulmonary arterial…
Design
Preclinical
Authors
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Suggests pulmonary baroreflex involvement in pressor responses; leaves open translation to human exercise or pulmonary hypertension.
Does stimulation of pulmonary arterial baroreceptors evoke reflex cardiovascular and respiratory responses in anaesthetised dogs?
Stimulation of pulmonary arterial baroreceptors evokes a pressor reflex and augments respiratory drive, which may play a role in the cardio-respiratory response to exercise and in conditions like pulmonary hypertension.
McMahon et al. (2000) studied this question.
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