18F-FDG PET/CT can comprehensively evaluate both paraganglioma and right ventricular metabolic changes in patients with cyanotic heart disease and Eisenmenger syndrome.
May support 18F-FDG PET/CT for dual assessment in Eisenmenger syndrome; leaves open prospective validation.
There is emerging evidence linking cyanotic heart disease and pheochromocytoma-paraganglioma through a proposed hypoxia pathway. We present a 59-year-old woman with known Eisenmenger syndrome secondary to delayed diagnosis of ventricular septal defect, in whom F-FDG PET/CT provided comprehensive evaluation of both an F-FDG-avid left glomus vagale paraganglioma and also increased right ventricular myocardial glucose metabolism in response to severe pulmonary hypertension in the chronic shunting state.
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Hsu et al. (2015) studied this question.
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