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February 6, 2008Clinical Journal of the American Society of Nephrology

Kidney Transplantation as Primary Therapy for End-Stage Renal Disease

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Authors

MAMichaël AbécassisSBStephen T. BartlettACAllan J. Collins

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Overview

Consensus conference report reveals systemic barriers limiting preemptive kidney transplantation in end-stage renal disease, highlighting the need for earlier education and timely donor evaluation.

Key Points

  • To examine why early kidney transplantation is rarely used as the primary therapy for end-stage renal disease and identify strategies to overcome barriers to its adoption.
  • Convened the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (KDOQI) conference in Washington, DC, on March 19–20, 2007.
  • Engaged 52 expert participants representing transplant centers, dialysis providers, and payers across three work groups focusing on clinical paradigms, education, and health care financing.
  • Observed that only 2.5% of incident patients with end-stage renal disease receive a kidney transplant as their initial modality of renal replacement therapy, remaining static for over a decade.
  • Identified critical systemic barriers across educational, clinical, and financial domains, recommending simultaneous transplant evaluation during vascular access referral to expand access to early living donor transplantation.

Cite This Study

Abécassis et al. (2008) studied this question.

synapsesocial.com/papers/6a8ec69bc2a8a91e7c3be7echttps://doi.org/10.2215/cjn.05021107
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Why Do Preemptive Kidney Transplant Recipients Have an Allograft Survival Advantage?2004 · 96 citations
  2. 2Waiting time on dialysis as the strongest modifiable risk factor for renal transplant outcomes2002 · 784 citations
  3. 3Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric Transplant1999 · 5,398 citations
  4. 4Geographic Variability in Access to Primary Kidney Transplantation in the United States, 1996–20052007 · 138 citations