Key result
Highest uric acid-to-HDL ratio linked to ~8.5-fold greater diabetes risk in women.
Why the study?
Is the uric acid to high-density lipoprotein cholesterol ratio (UHR) associated with diabetes risk, and does this association differ by gender?
Cross-Sectional (n=6,843)
Yes
Is the uric acid to high-density lipoprotein cholesterol ratio (UHR) associated with diabetes risk, and does this association differ by gender?
Odds Ratio: 8.494 (95% CI 5.542–13.019)
p-value: p=<0.001
No takes yet. Share an insight, caveat, or question.
The uric acid to HDL cholesterol ratio is strongly associated with diabetes risk in women but not men, with insulin resistance acting as a primary mediator.
Yin et al. (2024) conducted a cross-sectional in Diabetes (n=6,843). Uric acid to high-density lipoprotein cholesterol ratio (UHR) vs. Lower UHR quartiles was evaluated on Diabetes risk (OR 8.494, 95% CI 5.542-13.019, p=<0.001). The highest quartile of the uric acid to high-density lipoprotein cholesterol ratio was associated with an 8.49-fold increased risk of diabetes in women (OR 8.494, 95% CI 5.542-13.019, p<0.001).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: