Key result
Cardiovascular manifestations were present in 58.3% of patients with rheumatoid arthritis, and these patients had a significantly higher rate of rheumatoid factor positivity (82.9% vs. 32.8%) compared to those without cardiovascular manifestations.
Why the study?
The increased inflammatory burden in rheumatoid arthritis may lead to atherosclerosis, myocardial infarction, and subsequent mortality, prompting investigation into the frequency of cardiovascular manifestations.
Cross-Sectional (n=322)
No
Absolute Event Rate: 82.9% vs 32.8%
p-value: p=< 0.0001
Over half of patients with rheumatoid arthritis exhibited cardiovascular manifestations, which were significantly associated with higher inflammatory markers and rheumatoid factor positivity, highlighting the need for routine cardiac screening in this population.
No takes yet. Share an insight, caveat, or question.
Supports routine cardiovascular screening in rheumatoid arthritis patients with positive rheumatoid factor; leaves open whether targeted.
Kumar et al. (2021) conducted a cross-sectional in Rheumatoid arthritis (n=322). Cardiovascular manifestations vs. No cardiovascular manifestations was evaluated on Rheumatoid factor positivity (p=< 0.0001). Cardiovascular manifestations were present in 58.3% of patients with rheumatoid arthritis, and these patients had a significantly higher rate of rheumatoid factor positivity (82.9% vs. 32.8%) compared to those without cardiovascular manifestations.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: