Key result
Ankylosing spondylitis without cardiac involvement was not associated with decreased aortic elasticity compared to healthy controls, nor did it correlate with disease duration or BASDAI.
Why the study?
Is aortic elasticity decreased in patients with ankylosing spondylitis without cardiac involvement compared to healthy controls?
Case-Control (n=36)
Single-blind
No
Is aortic elasticity decreased in patients with ankylosing spondylitis without cardiac involvement compared to healthy controls?
Absolute Event Rate: 8.53% vs 9.79%
p-value: p=>0.05
In Korean patients with ankylosing spondylitis without cardiac involvement, aortic elasticity measured by echocardiography was not significantly decreased compared to healthy controls and did not correlate with disease duration or activity.
No reduction in aortic elasticity in ankylosing spondylitis without cardiac involvement; leaves open whether longitudinal monitoring detects later vascular changes.
Objective: Cardiac manifestations are well recognized complication of ankylosing spondylitis (AS). They include aortic incompetence, conduction defects, mitral valve disease, pericarditis and cardiomyopathy. There was one study to evaluate the change of aortic elasticity in AS patient and the association between the aortic strain and duration of AS, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). We designed this study to determine whether aortic elasticity changes in Korean AS patients and is associated with the duration of AS or BASDAI.
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Kim et al. (2008) conducted a case-control in Ankylosing spondylitis (n=36). Ankylosing spondylitis vs. Healthy controls was evaluated on Aortic strain (%) (p=>0.05). Ankylosing spondylitis without cardiac involvement was not associated with decreased aortic elasticity compared to healthy controls, nor did it correlate with disease duration or BASDAI.
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