Observational (n=300)
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This historical case series describes the clinical features and primarily rheumatic etiology of severe aortic insufficiency in patients being evaluated for early artificial plastic aortic valves.
Article1 July 1957UNUSUAL CLINICAL FEATURES ASSOCIATED WITH SEVERE AORTIC INSUFFICIENCYW. PROCTOR HARVEY, M.D., JACK P. SEGAL, M.D., CHARLES A. HUFNAGEL, M.D.W. PROCTOR HARVEY, M.D.Search for more papers by this author, JACK P. SEGAL, M.D.Search for more papers by this author, CHARLES A. HUFNAGEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-1-27 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONDuring the last five years at Georgetown University Medical Center we have had the unique opportunity of evaluating over 300 patients with severe aortic insufficiency of various causes, the most common being rheumatic fever (over 80%). Most were seen for consideration of surgical correction of their lesions utilizing the artificial plastic aortic valve. The aortic insufficiency was severe and of an advanced degree. Practically all of the patients had progressive symptoms of cardiac decompensation or angina pectoris or both despite adequate medical therapy. It should be emphasized that only patients withseveredegrees of aortic insufficiency are included in...Bibliography1. Friedberg CK: Diseases of the heart, 1951, W. B. Saunders Co., Philadelphia. Google Scholar2. Christian HA: The diagnosis and treatment of disease of the heart, 1940, Oxford University Press, New York. Google Scholar3. Fishberg AM: Heart failure, 1940, Lea & Febiger, Philadelphia. Google Scholar4. Walsh WH: Disease of the heart, 1862, Lea and Blanchard, Philadelphia. Google Scholar5. Flaxman N: History of aortic insufficiency, Bull. Hist. Med. 7: 192, 1939. Google Scholar6. Corrigan DJ: On permanent patency of the mouth of the aorta, or inadequacy of the aortic valve, Edinburgh M. and S. J. 37: 225, 1832. MedlineGoogle Scholar7. CastlemanTowne BVW: Case No. 37501 of the Case Records of the Massachusetts General Hospital, New England J. Med. 245: 941, 1951. CrossrefMedlineGoogle Scholar8. MitchellSackettHunzickerLevine AMCHWJSA: Clinical features of aortic stenosis, Am. Heart J. 48: 684, 1954. CrossrefMedlineGoogle Scholar9. Cabot RC: Syphilitic aortitis and heart disease (case 14381), New England J. Med. 199: 946, 1928. CrossrefGoogle Scholar10. Langley GT: Aortic incompetence: a clinical study, Lancet 2: 1209, 1921. CrossrefGoogle Scholar11. Clinical Pathological Conference: Aortic insufficiency with cardiac failure and recurrent abdominal pain, Am. J. Med. 11: 507, 1951. CrossrefMedlineGoogle Scholar12: SchilderHarveyHufnagel DPWPCA: Rheumatoid spondylitis and aortic insufficiency, New England J. Med. 255: 11, 1956. CrossrefMedlineGoogle Scholar13. McKusick VA: The cardiovascular aspects of Marfan's syndrome: a heritable disorder of connective tissue, Circulation 11: 321, 1955. CrossrefMedlineGoogle Scholar14. SegalHarveyHufnagel JPWPCA: A clinical study of one hundred cases of aortic insufficiency, Am. J. Med. 21: 200, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.*Presented in part at the Thirty-seventh Annual Session of The American College of Physicians, Los Angeles, California, April 16, 1956.From the Departments of Medicine and Surgery, Georgetown University School of Medicine.Supported in part by grants H-1346 (C2) from the United States Public Health Service, National Institutes of Health, Bethesda, Maryland, and the Washington Heart Association.Requests for reprints should be addressed to W. Proctor Harvey, M.D., Georgetown University Medical Center, Washington 7, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHeterogeneity of myocardial blood flowEarly descriptions of aortic regurgitationCharacteristics of Coronary Artery Blood Velocity Waveforms in Aortic Stenosis and RegurgitationTransmural myocardial perfusionThe Evaluation of Patients for Prosthetic Valve ImplantationNoninvasive diagnosis of aortic and mitral valve disease with pulsed-doppler spectral analysisTotal and Transmural Perfusion of the Hypertrophied HeartClinical aspects of acquired valvular heart diseaseDie AorteninsuffizienzQualitative Morphology of Heart FailureREFERENCESSyndrome of acute hemorrhagic intestinal infarction and renal insufficiency following aortic valve replacement for aortic insufficiencyDie koronare Blutversorgung bei den Klappeninsuffizienzen des linken HerzensMassive Intestinal Infarction without Vascular Occlusion Associated with Aortic Insufficiency 1 July 1957Volume 47, Issue 1Page: 27-38KeywordsAnginaAortaLesionsMedical servicesPancreatitisPeptic ulcersRheumatic feverSpondylitisSurgeryThyroid Issue Published: 1 July 1957 PDF downloadLoading ...
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Harvey et al. (1957) conducted an observational in Severe aortic insufficiency (n=300). Severe aortic insufficiency was evaluated.
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