Key result
The lowest socioeconomic status was significantly associated with an increased risk of death (HR 1.95) and stroke (HR 2.04) compared to the highest socioeconomic status, particularly in individuals without renal dysfunction.
Why the study?
The effects of socioeconomic status on MACE in individuals with and without renal dysfunction had not been comprehensively explored in Korea.
Does low socioeconomic status increase the risk of myocardial infarction, stroke, and death in individuals with and without renal dysfunction?
Cohort (n=30,407)
Does low socioeconomic status increase the risk of myocardial infarction, stroke, and death in individuals with and without renal dysfunction?
Hazard Ratio: 1.95 (95% CI 1.59–2.4)
Absolute Event Rate: 25.89% vs 3.16%
p-value: p=<0.001
Lower socioeconomic status is independently associated with an increased risk of stroke and death, particularly in individuals without renal dysfunction.
Highlights socioeconomic disparities as a critical non-biological risk factor for stroke and mortality; leaves open.
BACKGROUND: Although multiple factors influence the risk of major adverse cardiovascular events (MACE), the effects of socioeconomic status on MACE in the presence and absence of renal dysfunction (RD) have not been comprehensively explored in Korea. METHODS: We examined the effects of socioeconomic status on MACE in individuals with and without RD. The data of 44,473 Koreans from 2008 to 2017 were obtained from the Health Care Big Data Platform of the Ministry of Health and Welfare in Korea. Their socioeconomic status was assessed using a socioeconomic score (SES) based on marital status, education, household income, and occupation. The incidence of myocardial infarction (MI), stroke, and death was compared according to SES level (0-4). Multiple linear regression analysis was used to evaluate the hazard ratios and 95% confidence intervals for outcomes based on participant SES. RESULTS: MI risk was only affected by education level. The participants' income, education, and SES affected their stroke risk, whereas death was associated with all four socioeconomic factors. The incidence of stroke and death increased as SES worsened (from 0 to 4). SES was positively related to risk of stroke and death in participants without RD. SES did not affect MI, stroke, or death in participants with RD. CONCLUSION: A low socioeconomic status is associated with risk of stroke and death, especially in individuals without RD.
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Bae et al. (2023) conducted a cohort in General population (n=30,407). Low socioeconomic status vs. High socioeconomic status was evaluated on Death (HR 1.95, 95% CI 1.59-2.40, p=<0.001). The lowest socioeconomic status was significantly associated with an increased risk of death (HR 1.95) and stroke (HR 2.04) compared to the highest socioeconomic status, particularly in individuals without renal dysfunction.
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